Why the study?
Is elevated serum xanthine oxidase activity associated with the development of Type 2 Diabetes?
Is elevated serum xanthine oxidase activity associated with the development of Type 2 Diabetes?
Elevated serum xanthine oxidase activity is associated with an increased risk of developing type 2 diabetes, independent of uric acid concentration.
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Elevated XO activity may flag T2DM risk beyond UA; hypothesis-generating and requires trials before any clinical use.
Elevated serum XO activity, but not UA concentration, was associated with an increased risk of developing T2DM in women and men with mutual adjustment for XO and UA. Further studies are needed to examine the underlying mechanisms.
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Li et al. (2018) studied this question.
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