Why the study?
Does measurement of PFR and PIMR using TPSG detect progressive pulmonary microvascular obstruction?
Does measurement of PFR and PIMR using TPSG detect progressive pulmonary microvascular obstruction?
Novel thermodilution-derived indices (PFR and PIMR) can detect pulmonary microvascular obstruction, offering a potential new method for assessing the pulmonary microcirculation.
Thermodilution-derived mean transit time can be accurately and reproducibly measured in the pulmonary circulation using TPSG. Mean transit time-derived PFR and PIMR can be assessed using a TPSG and adenosine or papaverine as hyperemic agents. These novel indices detect progressive pulmonary microvascular obstruction and thus have with a potential role for pulmonary microcirculatory assessment in humans.
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Ilsar et al. (2010) studied this question.
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