Outcomes of renal cell carcinoma with associated venous tumor thrombus: experience from a large cohort and short time span in a single center

Zhigang Chen; Feilong Yang; Liyuan Ge; Min Qiu; Zhuo Liu; Cheng Liu; Xiaojun Tian; Shudong Zhang; Lulin Ma

doi:10.1186/s12885-021-08508-x

July 2, 2021BMC CancerOpen Access

Outcomes of renal cell carcinoma with associated venous tumor thrombus: experience from a large cohort and short time span in a single center

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Key Points

To evaluate overall survival and determine independent prognostic predictors in patients with renal cell carcinoma presenting with venous tumor thrombus.
Evaluated clinical and survival outcomes in a single-center cohort of patients with renal cell carcinoma and associated venous tumor thrombus treated over a short time span.
Overall survival was poor in patients diagnosed with renal cell carcinoma and accompanying venous tumor thrombus.
Positive lymph nodes, metastasis at surgery, tumor necrosis, and sarcomatoid differentiation were identified as independent prognostic predictors, whereas anatomical venous tumor thrombus level was not.

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Implication

Cohort study reveals poor survival in renal cell carcinoma with venous tumor thrombus, indicating tumor biology outweighs thrombus level as a prognostic predictor.

Abstract

The OS was poor for patients with RCC with VTT. Rather than VTT level, positive lymph node, metastasis at surgery, tumor necrosis and sarcomatoid differentiation were independent prognostic predictors.

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Chen et al. (2021) studied this question.

synapsesocial.com/papers/69d721f2236f4746d4563a12 https://doi.org/10.1186/s12885-021-08508-x

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Outcomes of renal cell carcinoma with associated venous tumor thrombus: experience from a large cohort and short time span in a single center

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Outcomes of renal cell carcinoma with associated venous tumor thrombus: experience from a large cohort and short time span in a single center

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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