Why the study?
Does coronary sinus occlusion reduce mortality and infarct size following sudden left anterior descending artery occlusion in dogs?
Population
Dogs weighing approximately 15 kilos subjected to sudden occlusion of the left anterior descending branch
Comparison
Coronary sinus occlusion, either complete or… vs Sudden occlusion of the left anterior descending…
Design
Preclinical
Follow-up
average 1 week
Authors
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Coronary sinus occlusion merits testing in human acute MI; animal data leave translation to clinical outcomes open.
Does coronary sinus occlusion reduce mortality and infarct size following sudden left anterior descending artery occlusion in dogs?
Partial persistent coronary sinus occlusion experimentally reduces mortality and infarct size following subsequent sudden LAD occlusion in dogs.
Gross et al. (1937) studied this question.
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