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September 2, 2016Clinical ChemistryOpen Access

Detection of KRAS Mutations in Circulating Tumor DNA by Digital PCR in Early Stages of Pancreatic Cancer

Nora Brychta Thomas Krahn Oliver von Ahsen

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Abstract

Our results support further evaluation of tumor specific mutations as early diagnostic biomarkers using plasma samples as liquid biopsy.

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Brychta et al. (2016) studied this question.

synapsesocial.com/papers/69d72b4866e6af6209f5082e https://doi.org/10.1373/clinchem.2016.257469

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Cancer statistics, 2016Registry Study · 2016 · 16,008 citations
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4Detection and quantification of mutations in the plasma of patients with colorectal tumorsDiagnostic Study · 2005 · 1,188 citations
5Circulating Nucleic Acids and Critical IllnessOriginal Research · 2006 · 48 citations

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