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Systematic review reveals increased risk of complications in pregnant women with thyroid dysfunction, highlighting the need for clinical trials on early treatment.
Pregnant women with subclinical hypothyroidism or thyroid antibodies have an increased risk of complications, especially pre-eclampsia, perinatal mortality and (recurrent) miscarriage. Future research, within the setting of clinical trials, should focus on the potential health gain of identification, and effect of treatment, of thyroid disease on pregnancy outcome.
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Boogaard et al. (2011) studied this question.
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