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March 12, 2014Malaria JournalOpen Access

Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria

Katherine Plewes A. A. N. M. Royakkers Josh Hanson Md Mahtab Uddin Hasan Shamsul Alam Aniruddha Ghose Richard J. Maude Pauline M. C. Stassen Prakaykaew Charunwatthana Sue J. Lee Gareth Dh Turner Arjen M. Dondorp Marcus J. Schultz

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Abstract

Both sequestered parasite burden and immune activation contribute to the pathogenesis of AKI in severe falciparum malaria.

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Plewes et al. (2014) studied this question.

synapsesocial.com/papers/69d732473f2a6ac123b8a43d https://doi.org/10.1186/1475-2875-13-91

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Acute Renal Failure in Patients with Severe Falciparum MalariaOriginal Research · 1992 · 199 citations
2Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized TrialPrognostic Study · 2012 · 195 citations
3Falciparum malaria associated with jaundice, renal failure and anaemiaOriginal Research · 1971 · 17 citations
4A quantitative ultrastructural study of renal pathology in fatal<i>Plasmodium falciparum</i>malariaOriginal Research · 2007 · 126 citations
5Stage-dependent production and release of histidine-rich protein 2 by Plasmodium falciparumOriginal Research · 2005 · 122 citations

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