June 12, 2013Open Access

Aldosterone, C-Reactive Protein, and Plasma B-Type Natriuretic Peptide Are Associated With the Development of Metabolic Syndrome and Longitudinal Changes in Metabolic Syndrome Components

Structured PICO

Are circulating aldosterone, CRP, and BNP concentrations associated with the development of metabolic syndrome in African Americans?

Population

African Americans (AAs)

Intervention

Circulating aldosterone, C-reactive protein (CRP), and plasma B-type natriuretic peptide (BNP) concentrations

Outcome

Incident metabolic syndrome (MetS) and longitudinal changes in MetS componentssurrogate

Elevated aldosterone and CRP predict the development of metabolic syndrome in African Americans, while BNP exhibits a novel U-shaped relationship with metabolic syndrome components.

Abstract

Our analysis confirms that, in AAs, higher circulating aldosterone and CRP concentrations predict incident MetS. The nonlinear U-shape relation of BNP with MetS and its components has not been reported before and thus warrants replication.

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Cite This Study

Musani et al. (Wed,) studied this question.

synapsesocial.com/papers/69d73a565f9a1dad5348f7ee https://doi.org/https://doi.org/10.2337/dc12-2562

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