Does the estimated glucose disposal rate (eGDR) index outperform other insulin resistance surrogates in predicting incident cardiovascular diseases in individuals with CKM syndrome stages 0-3?
The eGDR index is a superior surrogate marker for insulin resistance compared to other indices for predicting incident cardiovascular events in early-stage cardiovascular-kidney-metabolic syndrome.
The eGDR index outperforms six other IR indices in predicting CVD, heart disease, and stroke in individuals with CKM syndrome stages 0-3. Its incorporation into predictive models enhances risk stratification and may aid in the early identification of high-risk individuals in this population. Further studies are needed to validate these findings in external cohorts.
Dong et al. (Wed,) studied this question.
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