Why the study?
Does pernicious anemia increase the risk of subsequent cancer?
Does pernicious anemia increase the risk of subsequent cancer?
Pernicious anemia is associated with an increased risk of gastric carcinoma, carcinoid tumors, and potentially esophageal and other cancers.
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May inform gastric surveillance considerations in pernicious anemia; extends observational associations but leaves broader susceptibility open for validation.
This study confirms the excess risk of gastric carcinoma and carcinoid tumors associated with pernicious anemia, and suggests that the susceptibility state may extend to esophageal and other cancers.
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Hsing et al. (1993) studied this question.
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