American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

David R. Anderson; Gian Paolo Morgano; Carole Bennett; Francesco Dentali; Charles W. Francis; David García; Susan R. Kahn; Maryam Rahman; Anita Rajasekhar; Frederick B. Rogers; Maureen A. Smythe; Kari A.O. Tikkinen; Adolph J. Yates; Tejan Baldeh; Sara Balduzzi; Jan Brożek; Itziar Etxeandia‐Ikobaltzeta; Herman Johal; Ignacio Neumann; Wojtek Wiercioch; Juan José Yepes-Núñez; Holger J. Schünemann; Philipp Dahm

doi:10.1182/bloodadvances.2019000975

Why the study?

What are the optimal strategies for the prevention of venous thromboembolism in surgical hospitalized patients?

Key Points

Provide evidence-based clinical recommendations from the American Society of Hematology for the prevention of venous thromboembolism in surgical hospitalized patients.
An expert guideline panel formulated conditional recommendations regarding mechanical and pharmacological thromboprophylaxis for patients undergoing major surgical procedures.
Recommends mechanical prophylaxis over no prophylaxis and pneumatic compression over graduated compression stockings, while advising against inferior vena cava filters for major surgery generally.
Recommends either aspirin or anticoagulants—preferring direct oral anticoagulants over low-molecular-weight heparin—for joint arthroplasty, and supports pharmacological prophylaxis for major general, trauma, and gynecological surgery.
Advises against pharmacological prophylaxis in major neurosurgery, transurethral resection of the prostate, and radical prostatectomy.

Structured PICO

What are the optimal strategies for the prevention of venous thromboembolism in surgical hospitalized patients?

P

Population

Surgical hospitalized patients (including those undergoing major surgery, total hip or total knee arthroplasty, major general surgery, major neurosurgery, transurethral resection of the prostate, radical prostatectomy, major trauma surgery, or major gynecological surgery)

I

Intervention

Venous thromboembolism prophylaxis strategies (including mechanical prophylaxis, pneumatic compression, aspirin, direct oral anticoagulants, low-molecular-weight heparin, and unfractionated heparin)

C

Comparator

No prophylaxis or alternative prophylaxis strategies (e.g., graduated compression stockings, inferior vena cava filters)

O

Outcome

Prevention of venous thromboembolism

The 2019 ASH guidelines provide conditional recommendations for VTE prophylaxis tailored to specific surgical patient populations, favoring mechanical or pharmacological prophylaxis in high-risk groups while advising against pharmacological prophylaxis in certain bleeding-prone surgeries.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Informs procedure-specific VTE prophylaxis decisions; extends prior guidelines with conditional recommendations for surgical populations.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Anderson et al. (2019) studied this question.

synapsesocial.com/papers/69d73c743f2a6ac123b8acbf https://doi.org/10.1182/bloodadvances.2019000975

View Full Paper

Ask AI

Bookmark

Share

American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading