Observational analysis demonstrates distinct stages of HIV-1 viremia and seroconversion in plasma donors, highlighting improved staging for clinical trials and early diagnosis.
The sequential emergence of assay reactivity allows the classification of primary HIV-1 infection into distinct laboratory stages, which may facilitate the diagnosis of recent infection and stratification of patients enrolled in clinical trials. Quantitative analysis of preseroconversion replication rates of HIV is useful for projecting the yield and predictive value of assays targeting primary HIV infection.
No takes yet. Share an insight, caveat, or question.
Fiebig et al. (2003) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: