Experimental study maps GLP-1 receptor-expressing cells in the central nervous system of mice, highlighting a targeted viral approach for future functional analyses.
This study is a comprehensive description and phenotypic analysis of GLP-1R expression in the mouse CNS. We demonstrate the power of combining the GLP-1R-CRE mouse with a virus to generate a selective molecular handle enabling future in vivo investigation as to their physiological importance.
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Cork et al. (2015) studied this question.
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