At this time, PSA cutoff values (>2.5, 3.0 or 4.0 ng/ml) provide a reasonable balance between excessive detection rates and the risk of missing relevant prostate cancer. Men presenting with PSA values of 2.0-3.0 ng/ml should be reexamined more frequently. Available nomograms applying risk modifiers should be used specifically in this category of men.
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Schröder et al. (2009) studied this question.
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