February 18, 2022Open Access

The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification

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Resumen

Chinese head PDAC contained more KRAS G12V mutation than Western population. The well-performed nomogram may improve post-operation care in real-world practice.

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Yang et al. (Fri,) studied this question.

synapsesocial.com/papers/69d759eeb843b2be9948f57a https://doi.org/https://doi.org/10.1186/s12885-022-09279-9

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1Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development2011 · 773 citations
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4A phase I/II multiple expansion cohort trial of MRTX849 in patients with advanced solid tumors with KRAS G12C mutation.2019 · 36 citations
5Phase 1 study evaluating the safety, tolerability, pharmacokinetics (PK), and efficacy of AMG 510, a novel small molecule KRASG12C inhibitor, in advanced solid tumors.2019 · 173 citations

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