Why the study?
Is the plasma concentration of adiponectin higher in women with severe preeclampsia compared to normal pregnant women?
Is the plasma concentration of adiponectin higher in women with severe preeclampsia compared to normal pregnant women?
Elevated adiponectin in severe preeclampsia may represent a compensatory feedback mechanism to the metabolically-altered, anti-angiogenic, and pro-atherogenic state of the condition.
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Suggests compensatory response in severe preeclampsia; leaves open biomarker or mechanistic role pending validation.
Women with severe preeclampsia have a higher median plasma concentration of adiponectin than that of normal pregnant women. This may reflect a compensatory feedback mechanism to the metabolically-altered, anti-angiogenic and pro-atherogenic state of severe preeclampsia.
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Nien et al. (2007) studied this question.
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