Does Tissue Doppler Index E/e' reliably estimate left ventricular filling pressure and identify/exclude diastolic dysfunction/HFpEF in patients with preserved ejection fraction?
The diagnostic accuracy of Tissue Doppler Index E/e' for evaluating left ventricular filling pressure and HFpEF is limited, challenging its standalone reliability.
There is insufficient evidence to support that E/e' can reliably estimate LVFP in preserved EF. The diagnostic accuracy of E/e' to identify/exclude elevated LVFP and DD/HFpEF is limited and requires further validation in a well-designed prospective clinical trial.
Sharifov et al. (Wed,) studied this question.