Why the study?
Does surgical removal of inflamed epididymal white adipose tissue attenuate the development of NASH in obesity?
Does surgical removal of inflamed epididymal white adipose tissue attenuate the development of NASH in obesity?
Surgical removal of inflamed epididymal white adipose tissue attenuates NASH development, suggesting a causal role for eWAT in NASH pathogenesis.
Suggests causal role of inflamed eWAT in NASH; hypothesis-generating for human translation.
Intervention in NAFLD progression by removal of inflamed eWAT attenuates the development of NASH and reduces plasma levels of specific inflammatory mediators (cytokines and lipids). These data support the hypothesis that eWAT is causally involved in the pathogenesis of NASH.
No takes yet. Share an insight, caveat, or question.
Mulder et al. (2015) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: