Why the study?
Do DOACs carry a higher bleeding risk compared to VKAs in trauma patients?
Do DOACs carry a higher bleeding risk compared to VKAs in trauma patients?
In trauma patients, DOACs do not carry a higher bleeding risk than VKAs, and specific antagonists facilitate individualized bleeding management.
May guide trauma anticoagulation choices; leaves open confirmation of equivalent bleeding risk in prospective trials.
Current guidelines recommend the measurement of DOAC plasma levels in trauma patients. Compared to VKAs, DOACs do not carry a higher bleeding risk. DOAC specific antagonists facilitate the individual bleeding management.
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Schöchl et al. (2024) studied this question.
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