This study demonstrates that chylomicronemia induces atherosclerosis in mice and identifies GPIHBP1 as essential for the lipolytic processing of apo-B48 and apo-B100 lipoproteins.
Chylomicronemia may promote atherosclerosis; leaves open GPIHBP1's role in human disease.
Chylomicronemia causes atherosclerosis in mice. Also, we found that GPIHBP1 is required for the lipolytic processing of both apo-B48- and apo-B100-containing lipoproteins.
No takes yet. Share an insight, caveat, or question.
Weinstein et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: