Why the study?
Angiosarcomas exhibit aggressive clinical phenotypes with limited treatment options and poor outcomes, prompting investigation into the clinical relevance of systemic and intra-tumoral immune responses.
Does a high peripheral blood neutrophil-to-lymphocyte ratio (NLR) predict worse overall survival in patients with angiosarcoma?
Population
150 patients with angiosarcoma
Comparison
High vs low peripheral blood neutrophil-to-lymphocyte ratio
Design
Cohort study
Authors
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High NLR was associated with worse OS in angiosarcoma; hypothesis-generating for risk stratification and requires prospective validation.
Does a high peripheral blood neutrophil-to-lymphocyte ratio (NLR) predict worse overall survival in patients with angiosarcoma?
High peripheral blood neutrophil-to-lymphocyte ratio is associated with worse overall survival and correlates with intra-tumoral immune profiles and chemotherapy response in patients with angiosarcoma.
Chan et al. (2021) studied this question.
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