Soluble High Mobility Group Box 1 (HMGB1) Is a Promising Biomarker for Prediction of Therapy Response and Prognosis in Advanced Lung Cancer Patients

Nikolaus Handke; Alexander Rupp; Nicolai Trimpop; Joachim von Pawel; Stefan Holdenrieder

doi:10.3390/diagnostics11020356

February 20, 2021SHILAP Revista de lepidopterologíaOpen Access

Soluble High Mobility Group Box 1 (HMGB1) Is a Promising Biomarker for Prediction of Therapy Response and Prognosis in Advanced Lung Cancer Patients

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Key Points

To assess the clinical utility of soluble high mobility group box 1 (HMGB1) as a predictive and prognostic biomarker in advanced non-small cell lung cancer (NSCLC).
Evaluated circulating levels of soluble HMGB1 in patients diagnosed with advanced NSCLC to assess associations with treatment efficacy and patient outcomes.
Soluble HMGB1 levels predict therapeutic response in advanced NSCLC.
Circulating soluble HMGB1 serves as a viable prognostic indicator for patient survival outcomes.

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Implication

Clinical evaluation reveals soluble HMGB1 predicts therapy response and prognosis in advanced NSCLC, indicating its potential as an actionable monitoring biomarker.

Abstract

Soluble HMGB1 is a promising biomarker for prediction of therapy response and prognosis in advanced NSCLC patients.

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Handke et al. (2021) studied this question.

synapsesocial.com/papers/69d77c565f9a1dad5349056b https://doi.org/10.3390/diagnostics11020356

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Soluble High Mobility Group Box 1 (HMGB1) Is a Promising Biomarker for Prediction of Therapy Response and Prognosis in Advanced Lung Cancer Patients

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Soluble High Mobility Group Box 1 (HMGB1) Is a Promising Biomarker for Prediction of Therapy Response and Prognosis in Advanced Lung Cancer Patients

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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