It is shown that double inversion recovery used for water suppression can be made much less sensitive to pulse imperfections and to the variations in the relaxation times than a single inversion recovery. This insensitivity results in up to 10-fold improvement in the water suppression in vivo. The excellent water suppression by double inversion recovery is demonstrated experimentally by the in vivo proton spectra obtained from a rat brain.
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Shen et al. (1993) studied this question.
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