Does the development and timing of acute kidney injury requiring renal replacement therapy impact survival in patients with severe acute respiratory failure receiving extracorporeal membrane oxygenation?
In patients with severe acute respiratory failure receiving ECMO, acute kidney injury requiring renal replacement therapy prior to ECMO insertion is negatively associated with survival, whereas AKI developing during ECMO support is not.
Acute kidney injury is a major complication in acute respiratory distress syndrome probably mirroring severe systemic disease. In our cohort, development of acute kidney injury requiring renal replacement therapy prior to extracorporeal membrane oxygenation insertion was negatively associated with survival, whereas acute kidney injury that developed during extracorporeal membrane oxygenation support was not.
Haneya et al. (Thu,) studied this question.