Vascular Enhancement in Early Dynamic Liver MR Imaging in an Animal Model: Comparison of Two Injection Regimen and Two Different Doses Gd-EOB-DTPA (Gadoxetic Acid) With Standard Gd-DTPA

Despite the lower amount of gadolinium in the standard dose of Gd-EOB-DTPA, the results showed that the arterial enhancement in Gd-EOB-DTPA-enhanced dynamic liver MRI was comparable to Gd-DTPA. This result can be explained mainly by the higher relaxivity. Choosing a lower injection rate additionally supported to compensate for the lower injection volume by stretching the bolus without decreasing the peak. In this respect, an injection rate of 1 mL/s showed better results with regard to the arterial enhancement compared with 2 mL/s.