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December 8, 2015OncoImmunology364 citationsOpen Access

First oncolytic virus approved for melanoma immunotherapy

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JPJonathan PolGKGuido KroemerLGLorenzo Galluzzi

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Abstract

On 2015, October 27th, the US Food and Drug Administration (FDA) has officially approved talimogene laherparepvec (T-VEC, also known as OncoVEXGM-CSF) for use in melanoma patients with injectable but non-resectable lesions in the skin and lymph nodes. T-VEC (which is commercialized by Amgen, Inc. under the name of Imlygic®) becomes therefore the first oncolytic virus approved for cancer therapy in the US.

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Pol et al. (2015) studied this question.

synapsesocial.com/papers/69d78d556cc86f5f11b8a477https://doi.org/10.1080/2162402x.2015.1115641
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