January 1, 2017Clinical Laboratory

UGT1A1 Gene Polymorphism Predicts Irinotecan-Induced Severe Neutropenia and Diarrhea in Chinese Cancer Patients

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Abstract

In terms of irinotecan-based regimens in cancers, UGT1A1*6 plays a more vital role in hematologic toxicity (p = 0.011) whereas UGT1A1*28 get more involved in diarrhea (p < 0.001).

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Cite This Study

Peng et al. (2017) studied this question.

synapsesocial.com/papers/69d78dca5f9a1dad534907ea https://doi.org/10.7754/clin.lab.2017.170105

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Abstract

In terms of irinotecan-based regimens in cancers, UGT1A1*6 plays a more vital role in hematologic toxicity (p = 0.011) whereas UGT1A1*28 get more involved in diarrhea (p < 0.001).