Why the study?
Does age at menarche affect the incidence of myocardial infarction and ischemic stroke in postmenopausal women?
Does age at menarche affect the incidence of myocardial infarction and ischemic stroke in postmenopausal women?
Female reproductive factors, specifically age at menarche, exhibit distinct association patterns with MI and ischemic stroke and should be incorporated into cardiovascular risk assessments for postmenopausal women.
May inform menarche history in postmenopausal CV risk evaluation; leaves open causal mechanisms and intervention targets.
This study demonstrated different patterns of association between age at menarche and incidence of MI and IS: a linear association for MI versus a U-shaped association for IS. Female reproductive factors in addition to traditional cardiovascular risk factors should be considered when assessing overall cardiovascular risk in postmenopausal women.
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Jeong et al. (2023) studied this question.
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