A novel physiological model demonstrates that the influence of heartbeat and blood pressure on respiration is crucial for stable cardiorespiratory synchronization.
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Model evidence of heartbeat-respiration coupling for stable synchronization; leaves open human validation and clinical relevance.
Recent experimental studies suggest that there is evidence for a synchronization between human heartbeat and respiration. We develop a physiologically plausible model for this cardiorespiratory synchronization, and numerically show that the model can exhibit stable synchronization against given perturbations. In our model, in addition to the well-known influence of respiration on heartbeat, the influence of heartbeat (and hence blood pressure) on respiration is also important for cardiorespiratory synchronization.
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Kotani et al. (2002) studied this question.
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