Why the study?
Does higher dialysate calcium concentration cause more sympathetic stimulus during hemodialysis?
Does higher dialysate calcium concentration cause more sympathetic stimulus during hemodialysis?
While higher dialysate calcium concentration improves hemodynamic tolerability during hemodialysis, it increases sympathetic activity and decreases the ankle-brachial index.
Higher DCa may improve tolerability yet risks sympathetic activation and ABI decline; hypothesis-generating for optimal concentration in hemodialysis.
Although higher DCa is associated with better hemodynamic tolerability during hemodialysis, this occurs at the expense of increased sympathetic activity. Higher sympathetic activity was associated with a decrease of ABI during hemodialysis.
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Jimenez et al. (2016) studied this question.
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