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October 26, 2011Cytoskeleton

Interaction of low molecular weight hyaluronan with CD44 and toll‐like receptors promotes the actin filament‐associated protein 110‐actin binding and MyD88‐NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invasion

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Authors

LBLilly BourguignonSan Francisco VA Medical CenterGWGabriel WongAge UKCEChristine EarleSan Francisco VA Medical Center

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Bourguignon et al. (2011) studied this question.

synapsesocial.com/papers/69d7dae7a2a48916bbbee1f3https://doi.org/10.1002/cm.20544
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hyaluronan Binding by Cell Surface CD442000 · 387 citations
  2. 2Expression of CD44s, CD44v3 and CD44v6 in benign and malignant breast lesions: correlation and colocalization with hyaluronan2005 · 63 citations
  3. 3Serum hyaluronan (hyaluronic acid) in breast cancer patients1990 · 81 citations
  4. 4TLR-4 Signaling Promotes Tumor Growth and Paclitaxel Chemoresistance in Ovarian Cancer2006 · 493 citations
  5. 5New CD44 splice variants associated with human breast cancers1995 · 136 citations