A Systematic Review of Ultrasound-Detected Lipohypertrophy in Insulin-Exposed People with Diabetes

Haya Abu Ghazaleh; Rabab Hashem; Angus Forbes; Thandiwe Rebecca Dilwayo; María Duaso; Jackie Sturt; Susan Mary Halson-Brown; Henrietta Mulnier

doi:10.1007/s13300-018-0472-7

July 16, 2018Diabetes TherapyOpen Access

A Systematic Review of Ultrasound-Detected Lipohypertrophy in Insulin-Exposed People with Diabetes

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Why the study?

Does ultrasound improve the detection sensitivity of lipohypertrophy compared to clinical palpation in insulin-exposed people with diabetes?

Key Points

To assess the comparative detection sensitivity and clinical utility of ultrasound imaging versus manual palpation for identifying lipohypertrophy in people receiving insulin.
Systematic review synthesizing studies that evaluated ultrasound imaging alongside clinical palpation to detect lipohypertrophy sites in insulin-exposed populations with diabetes.
Available study evidence shows a lack of congruence regarding whether ultrasound demonstrates superior detection sensitivity compared with physical palpation for lipohypertrophy.
Current clinical evidence is insufficient to determine if routine palpation alone adequately identifies lipohypertrophic lesions or if ultrasound imaging is necessary to improve diagnostic precision.

Structured PICO

Does ultrasound improve the detection sensitivity of lipohypertrophy compared to clinical palpation in insulin-exposed people with diabetes?

P

Population

Insulin-exposed people with diabetes

I

Intervention

Ultrasound (US) for detection of lipohypertrophy (LH)

C

Comparator

Clinical palpation

O

Outcome

Detection sensitivity of lipohypertrophy (LH) sitessurrogate

Current evidence is inconclusive regarding whether ultrasound offers superior detection sensitivity for lipohypertrophy compared to clinical palpation in insulin-treated diabetes patients.

Limitations

Lack of robust study designs in current evidence

Implication

Inconclusive evidence on ultrasound versus palpation for lipohypertrophy; leaves open optimal detection in insulin-treated diabetes.

Abstract

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Cite This Study

Ghazaleh et al. (2018) studied this question.

synapsesocial.com/papers/69d7db7d05ee2ba81dbee5fb https://doi.org/10.1007/s13300-018-0472-7

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A Systematic Review of Ultrasound-Detected Lipohypertrophy in Insulin-Exposed People with Diabetes

Figures

Key Points

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

A Systematic Review of Ultrasound-Detected Lipohypertrophy in Insulin-Exposed People with Diabetes

Figures

Key Points

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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