Why the study?
Does the use of cerebral embolic protection devices reduce the occurrence of silent brain infarcts in patients undergoing TAVI?
Does the use of cerebral embolic protection devices reduce the occurrence of silent brain infarcts in patients undergoing TAVI?
Silent brain infarcts are common post-TAVI and negatively impact early cognitive outcomes, but current evidence does not show a significant reduction in SBIs with the use of cerebral embolic protection devices.
CEPD does not reduce silent brain infarcts in TAVI; confirms lack of benefit and questions routine use pending new trials.
Silent brain infarcts are common after TAVI; and diabetes, kidney disease, and pre-dilation increase overall SBI risk. While higher numbers of new SBIs appear to adversely affect early neurocognitive outcomes, long-term follow-up studies remain necessary as TAVI expands to low-risk patient populations. The use of CEPD did not result in a significant decrease in the occurrence of SBI.
No takes yet. Share an insight, caveat, or question.
Woldendorp et al. (2021) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: