Key result
Women receive less intensive lipid-lowering therapy and achieve LDL-C goals less often than men.
Why the study?
Are women less likely than men to receive and achieve goals with lipid-lowering therapy?
Are women less likely than men to receive and achieve goals with lipid-lowering therapy?
Answers are grounded in this paper and cite their sources.
Highlights a significant sex disparity in cardiovascular prevention, with women being systematically undertreated with lipid-lowering therapies compared to men.
Despite the proven efficacy of lipid-lowering therapy in both sexes, real-world studies indicate that women with comparable risk profiles are less likely than men to receive these treatments. Furthermore, women who are prescribed statins typically receive lower-intensity regimens than men and are less likely to achieve guideline-recommended low-density lipoprotein cholesterol goals. Despite advancements in lipid-lowering therapies, women compared to men, are systematically undertreated. This difference is influenced by patient-related, physician-related, and societal factors.
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Oortmerssen et al. (2025) conducted a review in Dyslipidemia. Female sex vs. Male sex was evaluated on Lipid-lowering therapy utilization and lipid goal attainment. Women are systematically undertreated with lipid-lowering therapies compared to men, receiving lower-intensity regimens and being less likely to achieve guideline-recommended LDL cholesterol goals.
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