Why the study?
New inflammatory biomarkers integrating leukocyte subgroups were devised, but their relationship with coronary artery disease severity and acute coronary syndrome occurrence needed evaluation.
Are the novel inflammatory biomarkers SII and SIRI associated with the severity of coronary artery disease and the occurrence of acute coronary syndrome?
Population
699 patients with acute coronary syndrome or stable CAD assessed with coronary angiography
Comparison
SII and SIRI levels across CAD severity and diagnosis groups
Authors
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SIRI association with STEMI and multivessel CAD is hypothesis-generating; leaves open incremental value for risk stratification in prospective studies.
Are the novel inflammatory biomarkers SII and SIRI associated with the severity of coronary artery disease and the occurrence of acute coronary syndrome?
The Systemic Inflammatory Response Index (SIRI) is significantly associated with the diagnosis of acute coronary syndrome and angiographic severity of coronary artery disease.
Dziedzic et al. (2022) studied this question.
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