Morphologies, that resemble viruses, were created using a single ABC triblock terpolymer poly(2-acryloylethyl-α-d-mannopyranoside)-b-poly(n-butyl acrylate)-b-poly(4-vinylpyridine) (PAcManA₇₀-b-PBA₃₆₉-b-PVP₃₇₀). Morphologies ranging from flower-like micelles, cylindrical micelles, raspberry-like morphologies to nanocaterpillars were obtained by adjusting the pH value during the self-assembly process. The resulting nanoparticles had an abundance of mannose on the surface, which were recognized by the mannose receptors of RAW264.7, a macrophage cell line that can be used as a model for virus entry.
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Dağ et al. (2015) studied this question.
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