Why the study?
What is the early risk of serious deterioration in patients with conservatively managed spontaneous coronary artery dissection?
What is the early risk of serious deterioration in patients with conservatively managed spontaneous coronary artery dissection?
Conservatively managed SCAD has a high early risk of clinical deterioration (1 in 6 patients within 6 days), particularly in those presenting with isolated intramural hematoma.
Supports close early monitoring in conservatively managed SCAD; leaves open whether isolated IMH requires distinct initial strategy.
Conservatively managed SCAD carries a 1:6 hazard for serious deterioration within 6 days. The risk was higher in those with isolated IMH at baseline. IMH often precedes development of intimal dissection, which has implications for mechanisms of SCAD.
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Waterbury et al. (2018) studied this question.
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