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January 29, 2016Human Brain MappingOpen Access

The effects of low‐dose ketamine on the prefrontal cortex and amygdala in treatment‐resistant depression: A randomized controlled study

Cheng‐Ta Li Mu‐Hong Chen Wei‐Chen Lin Chen‐Jee Hong Bang‐Hung Yang Ren‐Shyan Liu Pei‐Chi Tu Tung‐Ping Su

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Abstract

Ketamine's rapid antidepressant effects involved the facilitation of glutamatergic neurotransmission in the PFC.

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Li et al. (2016) studied this question.

synapsesocial.com/papers/69d836273eff0c9dfaae3a40 https://doi.org/10.1002/hbm.23085

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Pharmacological Aspects and Potential New Clinical Applications of Ketamine: Reevaluation of an Old DrugOriginal Research · 2009 · 190 citations
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4Development of a Rating Scale for Primary Depressive IllnessOriginal Research · 1967 · 8,412 citations
5Ketamine as a new treatment for depression: A review of its efficacy and adverse effectsNarrative Review · 2013 · 130 citations

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