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October 1, 2018The Journal of Rheumatology70 citations

Performance of Forced Vital Capacity and Lung Diffusion Cutpoints for Associated Radiographic Interstitial Lung Disease in Systemic Sclerosis

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KSKimberly ShowalterAHAileen HoffmannGRGerald Rouleau

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Abstract

Radiographic ILD is prevalent in SSc despite "normal" PFT. No % predicted FVC or DLCO threshold combinations yielded high NPV for SSc-ILD screening. "Normal" FVC and DLCO in patients with SSc, especially those with positive Scl-70 autoantibodies, should not obviate consideration of HRCT for ILD evaluation.

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Showalter et al. (2018) studied this question.

synapsesocial.com/papers/69d8397a8c03fbaff8bee37ahttps://doi.org/10.3899/jrheum.171362
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