Why the study?
Does thrombolytic therapy increase the risk of intracerebral hemorrhage or in-hospital mortality in patients with cancer and acute ischemic stroke?
Does thrombolytic therapy increase the risk of intracerebral hemorrhage or in-hospital mortality in patients with cancer and acute ischemic stroke?
Thrombolysis appears safe for acute ischemic stroke in patients with cancer, though efficacy may vary by cancer subtype.
May support thrombolysis in select cancer patients with stroke; leaves open need for randomized efficacy trials.
Thrombolytic therapy for acute stroke in patients with cancer is not associated with increased risk of intracerebral hemorrhage or in-hospital mortality. However, careful consideration of the cancer subtype may help delineate the subset of patients with poor response to thrombolysis. Prospective confirmation is warranted.
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Murthy et al. (2013) studied this question.
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