Why the study?
Does the use of Melody transcatheter valves or Contegra grafts increase the risk of infective endocarditis compared to homografts in right ventricular outflow tract conduits?
Does the use of Melody transcatheter valves or Contegra grafts increase the risk of infective endocarditis compared to homografts in right ventricular outflow tract conduits?
Melody transcatheter valves are associated with a significantly higher risk of infective endocarditis compared to homografts when used as right ventricular outflow tract conduits.
Melody valves were associated with higher endocarditis risk than homografts in RVOT conduits; leaves open optimal conduit selection pending prospective trials.
Bovine pulmonary conduits were more prone to endocarditis, with Melody valves being the most frequently infected. HRs for the risk of suffering from endocarditis were substantially higher for Melody valves and Contegra grafts compared to homografts, although this finding was only statistically significant for Melody valves and not for Contegra grafts.
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Gröning et al. (2019) studied this question.
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