Why the study?
Can clopidogrel hypersensitivity be successfully managed without drug interruption using short-course corticosteroids and antihistamines in patients post-PCI?
Can clopidogrel hypersensitivity be successfully managed without drug interruption using short-course corticosteroids and antihistamines in patients post-PCI?
Clopidogrel hypersensitivity can be safely managed without hazardous drug interruption by using short-course corticosteroids and antihistamines to build physiologic tolerance.
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May support uninterrupted clopidogrel post-PCI; hypothesis-generating from Level 5 evidence, requiring prospective trials.
Campbell et al. (2010) studied this question.
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