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July 28, 2012Clinical Cancer Research

Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK–Positive Non–Small Cell Lung Cancer

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Abstract

EGF-mediated activation of HER family signaling is associated with ALK-TKI resistance in lung cancer positive for EML4-ALK.

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Cite This Study

Tanizaki et al. (2012) studied this question.

synapsesocial.com/papers/69d849c85c3030ff03d19ae8 https://doi.org/10.1158/1078-0432.ccr-12-0392

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