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Synapse
June 5, 2007Circulation153 citationsOpen Access

Exercise Training Normalizes Sympathetic Outflow by Central Antioxidant Mechanisms in Rabbits With Pacing-Induced Chronic Heart Failure

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LGLie GaoWWWei WangDLDongmei Liu

Structured PICO

Does exercise training improve sympathetic outflow in rabbits with pacing-induced chronic heart failure?

P
Population
Rabbits with pacing-induced chronic heart failure
I
Intervention
Exercise training
O
Outcome
Sympathetic outflow and autonomic activitysurrogate

Exercise training normalizes sympathetic outflow in a rabbit model of chronic heart failure through central antioxidant mechanisms.

Abstract

These results suggest that an upregulation in central antioxidative mechanisms and suppressed central prooxidant mechanisms may contribute to the exercise training-induced beneficial effects on autonomic activity in CHF.

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Cite This Study

Gao et al. (2007) studied this question.

synapsesocial.com/papers/69d84dea5c3030ff03d19d3ahttps://doi.org/10.1161/circulationaha.106.677989
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Exercise on Coronary Endothelial Function in Patients with Coronary Artery Disease2000 · 1,344 citations
  2. 2Antiadrenergic Therapy of Chronic Heart Failure2003 · 91 citations
  3. 3Abnormalities of peripheral sympathetic nervous system control in congestive heart failure.1990 · 81 citations
  4. 4Inhibition of Geranylgeranylation Reduces Angiotensin II-Mediated Free Radical Production in Vascular Smooth Muscle Cells: Involvement of Angiotensin AT1 Receptor Expression and Rac1 GTPase2001 · 340 citations
  5. 5Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure1984 · 3,137 citations