Does the recombinant zoster vaccine reduce the risk of herpes zoster and subsequent venous thromboembolic events in patients with inflammatory arthritis on immunomodulatory treatment?
Vaccination against herpes zoster is supported in adults with inflammatory arthritis to reduce the risk of post-infection venous thromboembolic events.
This study showed that the effectiveness of Shingrix in patients with inflammatory arthritis on immunomodulatory treatment was 50%, and the risk of venous thromboembolic events was increased in the 60-90 days after herpes zoster, supporting the recommendation that adults with inflammatory arthritis should receive vaccination against herpes zoster to reduce the risk of such events.
Curtis et al. (Sat,) studied this question.