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March 22, 2016Diabetes Care240 citations

Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON

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MWMuh Geot WongVPVlado PerkovicJCJohn Chalmers

Key Points

  • The aim is to evaluate the long-term effects of intensive glucose control on the incidence of end-stage kidney disease (ESKD).
  • Conducted a randomized trial involving intensive glucose control strategies.
  • Monitored kidney function and cardiovascular outcomes over an extended follow-up period.
  • Assessed blood pressure levels and their relationship with kidney health.
  • Intensive glucose control led to a significant long-term reduction in ESKD incidence (exact rates not specified).
  • No increased risk of cardiovascular events or death was observed.
  • Benefits were more pronounced in participants with preserved kidney function and well-controlled blood pressure.

Abstract

Intensive glucose control was associated with a long-term reduction in ESKD, without evidence of any increased risk of cardiovascular events or death. These benefits were greater with preserved kidney function and with well-controlled blood pressure.

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Cite This Study

Wong et al. (2016) studied this question.

synapsesocial.com/papers/69d855e8d2f7327e70ae308bhttps://doi.org/10.2337/dc15-2322
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