Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON

Muh Geot Wong; Vlado Perkovic; John Chalmers; Mark Woodward; Qiang Li; Mark E. Cooper; Pavel Hamet; Stephen Harrap; Simon Heller; Stephen MacMahon; Giuseppe Mancia; Michel Marre; David R. Matthews; Bruce Neal; Neil R Poulter; Anthony Rodgers; Bryan Williams; Sophia Zoungas

doi:10.2337/dc15-2322

Key Points

The aim is to evaluate the long-term effects of intensive glucose control on the incidence of end-stage kidney disease (ESKD).
Monitored kidney function and cardiovascular outcomes over an extended follow-up period.
Assessed blood pressure levels and their relationship with kidney health.
Intensive glucose control led to a significant long-term reduction in ESKD incidence (exact rates not specified).
No increased risk of cardiovascular events or death was observed.
Benefits were more pronounced in participants with preserved kidney function and well-controlled blood pressure.

Abstract

Intensive glucose control was associated with a long-term reduction in ESKD, without evidence of any increased risk of cardiovascular events or death. These benefits were greater with preserved kidney function and with well-controlled blood pressure.

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Cite This Study

Wong et al. (2016) studied this question.

synapsesocial.com/papers/69d855e8d2f7327e70ae308b https://doi.org/10.2337/dc15-2322

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Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON

Key Points

Abstract

Discussion

Cite This Study

Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON

Key Points

Abstract

Discussion

Cite This Study

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