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January 5, 2017Proceedings of the National Academy of SciencesOpen Access

Mutational landscape of antibody variable domains reveals a switch modulating the interdomain conformational dynamics and antigen binding

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PKPatrick KoenigUniversity of California, MercedCLChingwei V. LeeGilead Sciences (United States)BWBenjamin T. WaltersRoche (United States)

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Koenig et al. (2017) studied this question.

synapsesocial.com/papers/69d85ffc33ca018b39ae39c0https://doi.org/10.1073/pnas.1613231114
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