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Synapse
May 12, 2016Molecular Neurodegeneration260 citationsOpen Access

Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

SSSofia SöllvanderENElisabeth NikitidouRBRobin Brolin

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Abstract

Taken together, our results suggest that astrocytes play a central role in the progression of Alzheimer's disease, by accumulating and spreading toxic Aβ species.

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Söllvander et al. (2016) studied this question.

synapsesocial.com/papers/69d88bfd18b0ca7f91d1816ahttps://doi.org/10.1186/s13024-016-0098-z
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