Online analysis of chemical components in heat-not-burn (HNB) cigarette aerosol is crucial for understanding the product's characteristics and guiding product development. Herein, a synchrotron radiation photoionization time-of-flight mass spectrometry method was established to online distinguish isobars and isomers in HNB cigarette aerosol, where photoionization efficiency (PIE) curves of HNB cigarette aerosol were scanned at different photon energies, and more than 43 components including aldehydes, ketones, alkenes, alkanes, and heterocyclic compounds were identified based on multiple linear regression (MLR) simulation. Additionally, the puff-by-puff dynamic evolutions of some typical components were investigated with the help of a smoking machine.
Lei et al. (Tue,) studied this question.