Pico-molar determination of lurasidone hydrochloride in pharmaceutical formulations using PVC-membrane bulk Miptode

Key Points

• This research aims to accurately measure very low concentrations of lurasidone hydrochloride using a specialized detection method.
• Used a molecularly imprinted polymer to enhance sensitivity.
• Developed a PVC-membrane bulk optode for optical detection.
• Focused on detecting picomolar concentrations of the drug.
• Successfully detected lurasidone hydrochloride at pico-molar levels.
• Demonstrated the effectiveness of the modified optode in pharmaceutical formulations.